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Spatial proteomics reveals phenotypic and functional differences in T cell and macrophage subsets during villitis of unknown etiology

9 Jan 2024

Abstract excerpt

Villitis of unknown etiology (VUE) is a prevalent inflammatory pathology of the placenta characterized by infiltration of maternal T cells and accumulation of fetal macrophages into chorionic villi. VUE is associated with a variety of adverse clinical outcomes, including fetal growth restriction and fetal demise. Evaluation of the phenotypic and functional differences between two immune cell types associated with...

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PMID: 38195710
DOI: 10.1038/s41598-024-51545-2

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