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Article

Trade-offs between receptor modification and fitness drive host-bacteriophage co-evolution leading to phage extinction or co-existence.

The ISME journal - 8 Jan 2024

Chen Lin, Zhao Xue, Wongso Shelyn, Lin Zhuohui, Wang Siyun

Abstract excerpt

Parasite-host co-evolution results in population extinction or co-existence, yet the factors driving these distinct outcomes remain elusive. In this study, Salmonella strains were individually co-evolved with the lytic phage SF1 for 30 days, resulting in phage extinction or co-existence. We conducted a systematic investigation into the phenotypic and genetic dynamics of evolved host cells and phages to elucidate...

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Source

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Identifiers

PMID: 39441988
DOI: 10.1093/ismejo/wrae214
PMCID: PMC11538992

Genes

SF1

Provenance

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