Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multisite binding of bacteriophages on lipopolysaccharides in Escherichia coli O157:H7 and the adaptive costs of phage resistance

17 Jun 2025

Abstract excerpt

ABSTRACT Escherichia coli ( E. coli ) O157:H7 is a major foodborne pathogen and a critical global food safety concern. Bacteriophage (phage) therapy offers a promising, highly specific biological alternative to antibiotic treatment. However, the clinical application of phage therapy is frequently limited by the rapid emergence of bacterial resistance. In this study, we examined the interaction between E. coli...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteriophages and microbial interactions
Share to Escherichia coli research studies
Share to Viral gastroenteritis research and epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40525839
DOI: 10.1128/spectrum.00067-25

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multisite binding of bacteriophages on lipopolysaccharides in Escherichia coli O157:H7 and the adaptive costs of phage resistancePMID 40525839Read ↗

Selective bacteriophages reduce the emergence of resistant bacteria in bacteriophage-antibiotic combination therapySemantic proximity Read ↗

Manipulating Interactions between T4 Phage Long Tail Fibers and Escherichia coli Receptors.Semantic proximity Read ↗

Selective bacteriophages reduce the emergence of resistant bacteria in the bacteriophage-antibiotic combination therapySemantic proximity Read ↗

Surface architecture of the bacterial envelope determines phage adsorption route in pathogenic <i>Escherichia coli</i> O157:H7Semantic proximity Read ↗

High-throughput mapping of the phage resistance landscape in E. coli.Semantic proximity Read ↗

High-throughput mapping of the phage resistance landscape in <i>E. coli</i>Semantic proximity Read ↗

Phages adapt to recognize an O-antigen polysaccharide site by mutating the “backup” tail protein ORF59, enabling reinfection of phage-resistant Klebsiella pneumoniaeSemantic proximity Read ↗

Variable fitness effects of bacteriophage resistance mutations in Escherichia coli: implications for phage therapy.Semantic proximity Read ↗

Lipopolysaccharide truncation and restoration drives a trade-off in resistance to two phages in <i>Pseudomonas aeruginosa</i>Semantic proximity Read ↗

Variable effects on virulence of bacteriophage resistance mechanisms in extraintestinal pathogenic <i>Escherichia coli</i>Semantic proximity Read ↗

Toward rational control of Escherichia coli O157:H7 by a phage cocktail.Semantic proximity Read ↗

Fitness costs of phage-driven resistance mutations in Salmonella Enteritidis populations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.