Article
Unraveling the complexity of skin's biological aging utilizing epigenetic clocks.
Clinical epigenetics - 9 Apr 2026
Bienkowska Agata, Qi Minyue, Kanta Konstantina, Del Pilar Bonilla-Tobar Maria, Völzke Henry, Gallinat Stefan, Jaspers Sören, Clemann Sven, Winnefeld Marc, Grönniger Elke, Kaderali Lars, Falckenhayn Cassandra
Abstract excerpt
BACKGROUND: DNA methylation (DNAm) plays a pivotal role in regulating gene expression and tissue function in the skin, which exhibits a high degree of responsiveness to environmental and lifestyle factors. These factors are believed to contribute to epigenetic drift, a hallmark of aging marked by increased methylation variability and changes in regulatory regions. While epigenetic clocks have advanced our...
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