Article
Powerful polymerases synthesize labeled RNA better, faster, stronger.
Trends in biochemical sciences - 1 Jul 2026
Khalique Aria A, Leconte Aaron M
Abstract excerpt
Engineered DNA polymerases capable of synthesizing RNA have the potential to make the synthesis of site-specifically labeled RNA faster, cheaper, and more user-friendly. After many years of trying, two recent reports, by Chen et al. and Medina et al., have identified new DNA polymerase mutants, which may unlock the promise of these enzymes for RNA production and research.
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