Article
A case of T-prolymphocytic leukemia harboring RAS mutation.
Annals of hematology - 9 Apr 2026
Perrone Salvatore, Pacitto Giada, Tirnetta Alessia, Mulargia Claudia, Angelitti Maria Rosaria, Corbingi Andrea, Ortu La Barbera Elettra, Fabiani Emiliano, Voso Maria Teresa, Di Napoli Arianna
Abstract excerpt
The text reports the clinical case of a 61-year-old woman with a long history of generalized pruritus who was eventually diagnosed with T-cell prolymphocytic leukemia (T-PLL), a rare and aggressive T-cell lymphoproliferative disorder. At presentation, the patient had fever, skin lesions, lymphocytosis, thrombocytopenia, coagulation abnormalities, and marked splenomegaly without lymphadenopathy. Morphological,...
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