Article
Management of prolymphocytic leukemia.
Hematology. American Society of Hematology. Education Program - 1 Jan 2015
Dearden Claire
Abstract excerpt
B-cell (B-PLL) and T-cell (T-PLL) prolymphocytic leukemias are rare, poor-prognosis lymphoid neoplasms with similar presentation characterized by symptomatic splenomegaly and lymphocytosis. They can be distinguished from each other and from other T- and B-cell leukemias by careful evaluation of morphology, immunophenotyping, and molecular genetics. The clinical behavior is typically aggressive, although a subset...
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