TNFRSF1A (-135 T>C, rs767455) Polymorphism as a Predictor of Radiation Induced Oral Mucositis and Treatment Response in Locally Advanced Head and Neck Cancer Patients.

doi:10.1002/hed.70277

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TNFRSF1A (-135 T>C, rs767455) Polymorphism as a Predictor of Radiation Induced Oral Mucositis and Treatment Response in Locally Advanced Head and Neck Cancer Patients.

Head & neck - 1 Sept 2026

Sarath Krishnan M P, Goyal Bela, Gupta Sweety, Gupta Amit, Mirza Anissa Atif

Abstract excerpt

INTRODUCTION: Head and neck squamous cell carcinoma (HNSCC) is the most common head and neck cancer in India, where intensity-modulated radiation therapy (IMRT) is the standard treatment. Despite therapeutic advances, variability in radiation response and toxicities persists. Genetic factors, including the TNFRSF1A (-135 T>C, rs767455) polymorphism, may influence susceptibility to oral mucositis, dermatitis, and...

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PMID: 41948912
DOI: 10.1002/hed.70277
PMCID: PMC13431857

Genes

TNFRSF1A
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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