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Association of CD40 gene polymorphisms and immune thrombocytopenic purpura in the adult Egyptian population

3 Aug 2022

Abstract excerpt

Background: The pathophysiology underlying primary adult immune thrombocytopenic purpura (ITP) has not yet been identified. However, many mechanisms affect the immune system, causing defective tolerance to self-platelets and megakaryocytes. Cluster of differentiation 40 (CD40) contributes to both humoral and cell-mediated immune responses. Methods: This case‒control study was conducted to detect rs4810485G>T and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35920091
DOI: 10.5045/br.2022.2022057

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