Article
The heterogeneity of Fuchs endothelial corneal dystrophy†.
The Journal of pathology - 1 Aug 2026
Patel Sangita P
Abstract excerpt
Late-onset Fuchs endothelial corneal dystrophy (FECD) is characterized by distinct extracellular matrix deposits (guttae) within the basement membrane (Descemet's membrane) of the corneal endothelium. In a recent study published in The Journal of Pathology, Vaitinadapoulé et al (2026) describe the diversity of guttae patterns in FECD through analysis of 500 Descemet's membrane specimens removed during surgery,...
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