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Genetic and Demographic Determinants of Fuchs Endothelial Corneal Dystrophy Risk and Severity

13 Mar 2025

Abstract excerpt

Importance: Understanding the pathogenic mechanisms of Fuchs endothelial corneal dystrophy (FECD) could contribute to developing gene-targeted therapies. Objective: To investigate associations between demographic data and age at first keratoplasty in a genetically refined FECD cohort. Design, Setting, and Participants: This retrospective cohort study recruited 894 individuals with FECD at Moorfields Eye Hospital...

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Identifiers

PMID: 40079965
DOI: 10.1001/jamaophthalmol.2025.0109

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