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Article

Pathological classification of Fuchs endothelial corneal dystrophy into several types and their relationships with CTG18.1 expansion repeats.

The Journal of pathology - 1 Jun 2026

Vaitinadapoulé Hanielle, Onitiu Daria, Maurin Corantin, Travers Gauthier, Crouzet Emmanuel, Dorado-Cortez Oliver, Poinard Sylvain, He Zhiguo, Forest Fabien, Ollier Edouard, Touraine Renaud, Gain Philippe, Perone Jean-Marc, Thuret Gilles

Abstract excerpt

Late-onset Fuchs endothelial corneal dystrophy (FECD) is the most common primary disease of the corneal endothelium and the leading indication for corneal transplantation in Western countries. It is characterized by progressive accumulation, over two to three decades, of extracellular matrix (ECM) components in Descemet's membrane (DM), leading to the formation of abnormal excrescences, known as guttae, and...

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Source

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Identifiers

PMID: 41736702
DOI: 10.1002/path.70044
PMCID: PMC13140138

Genes

TCF4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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