Article

Genetic and Demographic Determinants of Fuchs Endothelial Corneal Dystrophy Risk and Severity

2024-10-01

Abstract excerpt

<h4>Importance</h4> Understanding the pathogenic mechanisms of Fuchs endothelial corneal dystrophy (FECD) is essential for developing gene-targeted therapies. <h4>Objective</h4> To investigate associations between demographic data and age at first keratoplasty in a large genetically refined FECD cohort. <h4>Design, Setting, and Participants</h4> This retrospective cohort study recruited 894 individuals with FECD a...

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Literature Corpus work: dc0071ba-2fe2-50ea-bf35-9cad5c52577c
DOI: 10.1101/2024.09.29.24314217

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