Article

Pathological classification of Fuchs endothelial corneal dystrophy in several types and their relationships with CTG18.1 expansion repeats

2025-07-15

Abstract excerpt

Late-onset Fuchs endothelial corneal dystrophy (FECD) is the most common primary disease of the corneal endothelium and the leading indication for corneal transplantation in Western countries. It is characterized by the abnormal accumulation, over 2 to 3 decades, of extracellular matrix (ECM) components in the form of Descemet’s membrane (DM) excrescents, known as guttae, as well as additional DM layers. Clinical...

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Literature Corpus work: b17ea694-f3fc-52b2-a54f-c7603c86a064
DOI: 10.1101/2025.07.14.25330988

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