Article
Hypoxia Modulates Nanovesicle Phenotype and Angiogenic Function From Human Pluripotent Stem Cells.
Proteomics - 1 Jul 2026
Lozano Jonathan, Rai Alin, Phang Ren J, Cross Jonathon, Lim Shiang Y, Greening David W
Abstract excerpt
Nanovesicles (NVs)-generated directly from donor cells-have emerged as important mediators of intercellular communication, drug delivery devices, and in therapeutic applications, including regenerative biology. Top-down strategies to enhance the potential regenerative efficacy of NVs following cell hypoxic stress are poorly understood. Here, NVs were generated using rapid extrusion directly from human induced...
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