Article

Donor Age Impairs Vasculogenic Potential of hiPSC-Derived Endothelial Progenitors

2025-06-27

Abstract excerpt

<h4>Background</h4> Human induced pluripotent stem cells (hiPSCs) hold promise for vascular regeneration, but preliminary research often relies on neonatal donors, whereas clinical applications will use cells derived from older adults. Although the impact of donor age on reprogramming efficiency has been studied, its effect on the functionality of hiPSC-derived endothelial progenitors (hiPSC-EPs) remains unclear....

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Literature Corpus work: 598492cc-1ea9-5654-bee5-4cc1626f3b41
DOI: 10.1101/2025.06.24.661422

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