Article

Single-cell characterization of neovascularization using hiPSC-derived endothelial cells in a 3D microenvironment

2022-02-16

Abstract excerpt

The formation of vascular structures is fundamental for in vitro tissue engineering. Vascularization can enable the nutrient supply within larger structures and increase transplantation efficiency, which are currently limiting factors in organoid research. We differentiated human induced pluripotent stem cells toward endothelial cells in 3D suspension culture. To investigate in vitro neovascularization and vario...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4164675e-2c36-5b45-8e59-293e92164653
DOI: 10.1101/2022.02.15.480506

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Single-cell characterization of neovascularization using hiPSC-derived endothelial cells in a 3D microenvironmentDOI 10.1101/2022.02.15.480506Read

Recent Advances and Future Perspectives in Vascular Organoids and Vessel-on-ChipSemantic proximity Read

Differentiation Protocol-Dependent Variability in hiPSC-Derived Endothelial Progenitor FunctionalitySemantic proximity Read

Coordinated Development of Immune Cell Populations in Vascularized Skin Organoids from Human Induced Pluripotent Stem CellsSemantic proximity Read

Human Peripheral Blood-Derived Endothelial Colony-Forming Cells Are Highly Similar to Mature Vascular Endothelial Cells yet Demonstrate a Transitional Transcriptomic SignatureSemantic proximity Read

Vascular diseases await translation of blood vessels engineered from stem cellsSemantic proximity Read

ETV2 mediated differentiation of human pluripotent stem cells results in functional endothelial cells for engineering advanced vascularized microphysiological modelsSemantic proximity Read

Tissue microenvironment dictates the state of human induced pluripotent stem cell-derived endothelial cells of distinct developmental origin in 3D cardiac microtissuesSemantic proximity Read

Blood Vessel Resident Human Stem Cells in Health and DiseaseSemantic proximity Read

Fate and state transitions during human blood vessel organoid developmentSemantic proximity Read

Transcriptomic analysis of 3D vasculature-on-a-chip reveals paracrine factors affecting vasculature growth and maturationSemantic proximity Read

Transcriptomic Analysis of 3D Vasculature-On-A-Chip Reveals Paracrine Factors Affecting Vasculature Growth and MaturationSemantic proximity Read

Three-Dimensional Vascular Network Assembly From Diabetic Patient-Derived Induced Pluripotent Stem Cells.Semantic proximity Read