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Hypoxia-Preconditioned Human Dental Pulp Mesenchymal Stem Cell Secretome Enhances Tissue Regeneration in a Medicinal Leech Wound Model

2026-08-04

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Chronic and non-healing wounds remain a major clinical challenge due to persistent inflammation, impaired angiogenesis, and defective extracellular matrix (ECM) remodelling. Human Mesenchymal Stem Cells have emerged as promising regenerative therapies, with their effects mainly attributed to the secretome. In particular, the secretome, derived from human Denta...

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Literature Corpus work
c48f4390-3352-500f-babc-d71677b0eb5a
DOI
10.21203/rs.3.rs-10264893/v1
Open publication

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