Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Toward mutational epidemiology: using mutational signatures of environmental exposures to assess cancer risk.

Trends in cancer - 1 May 2026

Sherman Fiona, Rozowsky Jacob S, Okafor Arinze, Petljak Mia

Abstract excerpt

Exposure to environmental mutagens increases cancer risk, yet exposure-detection methods often lack standardization and sensitivity. Genotoxic agents leave characteristic 'mutational signatures' in DNA, creating permanent, quantitative records of past exposures. Analyses of these signatures have clarified the mutational impacts of many established carcinogens and implicated contributions of previously...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinogens
Share to DNA Mutational Analysis
Share to Environmental Exposure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutagenesis

Share to Mutagens

Share to Mutation

Share to Neoplasms

Share to Risk Assessment

Source

Identifiers

PMID: 41934048
DOI: 10.1016/j.trecan.2025.12.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Toward mutational epidemiology: using mutational signatures of environmental exposures to assess cancer risk.PMID 41934048Read ↗

Mutational epidemiology: achievements and expectations on enhancing our understanding of the causes of cancer.Semantic proximity Read ↗

Investigating the origins of the mutational signatures in cancer.Semantic proximity Read ↗

Molecular epidemiology of human cancer: biomarkers of genotoxic exposure and susceptibility.Semantic proximity Read ↗

Mutational signatures of environmental carcinogens in human tissue organoids revealed by duplex sequencing.Semantic proximity Read ↗

Molecular Epidemiology and the Genetics of Environmental CancerSemantic proximity Read ↗

Experimental investigations of carcinogen-induced mutation spectra: Innovation, challenges and future directions.Semantic proximity Read ↗

Implementing Mutational Epidemiology on a Global Scale: Lessons from Mutographs.Semantic proximity Read ↗

Molecular epidemiology and cancer: promising areas for future research in the post-genomic era.Semantic proximity Read ↗

Base changes in tumour DNA have the power to reveal the causes and evolution of cancer.Semantic proximity Read ↗

New horizons of DNA adductome for exploring environmental causes of cancer.Semantic proximity Read ↗

Molecular epidemiology: carcinogen-DNA adducts and genetic susceptibility.Semantic proximity Read ↗

Genome-scale mutational signature analysis in archived fixed tissues.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.