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Article

Association of a functional polymorphism in the MMP7 gene promoter with susceptibility to vulnerable carotid plaque in a Han Chinese population.

Clinical chemistry and laboratory medicine - 1 Oct 2011

Hu Xiao-Fei, Jin Xiao-Ping, Hu Pei-Yang, Zhu Min, Wang Feng, Lin Xian-Fang, Li Wei-Ling, Ni Hong, Yang Li-Hua

Abstract excerpt

BACKGROUND: Matrix metalloproteinase-7 (MMP-7) may play an important role in the development of vulnerable carotid plaque. An A-to-G transition (-181A/G) in the promoter region of MMP7 is functional in vitro by altering the transcriptional activity of the gene. The aim of this study was to investigate the association between the MMP7 -181A/G polymorphism and vulnerable carotid plaque formation. METHODS: The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21722074
DOI: 10.1515/CCLM.2011.241

Genes

MMP7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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