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Article

Evaluation of genetic variants in microRNA biosynthesis genes and risk of breast cancer in Chinese women.

International journal of cancer - 1 Nov 2013

Jiang Yue, Chen Jiaping, Wu Jiangping, Hu Zhibin, Qin Zhenzhen, Liu Xiao'an, Guan Xiaoxiang, Wang Yanru, Han Jing, Jiang Tao, Jin Guangfu, Zhang Mingfeng, Ma Hongxia, Wang Shui, Shen Hongbing

Abstract excerpt

MicroRNAs (miRNA) are a class of small, noncoding RNA molecules involved in a diversity of cellular functions. Single nucleotide polymorphisms (SNPs) in miRNA biosynthesis genes may affect the biogenesis of miRNAs and consequently affect the miRNAs regulation. In this study, we systematically selected 24 functional SNPs located in eight key biosynthesis genes of miRNA (DROSHA, DGCR8, RAN, DICER, AGO2, GEMIN3,...

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Identifiers

PMID: 23629745
DOI: 10.1002/ijc.28237

Genes

DGCR8
DROSHA
RAN
AGO2
GEMIN4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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