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Article

Immune dysfunction in psychiatric disorders: emerging genomic insights.

Current opinion in genetics & development - 1 Jun 2026

McGrath Isabelle M, Lynall Mary-Ellen

Abstract excerpt

Psychiatric disorders are polygenic conditions of the mind and brain, yet immune associations emerge across genetic and molecular studies. Some immune signals may reflect assay bias or illness effects; immunogenetic approaches help disentangle cause and correlation. Genetic associations in the extended major histocompatibility complex (MHC) remain of unclear relevance to immunopathogenesis but warrant...

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PMID: 41924839
DOI: 10.1016/j.gde.2026.102467

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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