Functional immunogenomics and deep clinical phenotyping to resolve the challenges of heterogeneity in mental disorders.

Abstract excerpt

Historically, the field of psychiatry has relied on descriptive categories, as outlined in the Diagnostic and Statistical Manual of Mental Disorders (DSM) or International Classification of Diseases (ICD). However, with increasing knowledge of molecular processes that contribute to mental disorders, the descriptive approach has been criticised. The current descriptive diagnostic categories lack sensitivity and...

Topics

• Humans
• Mental Disorders
• Phenotype
• Immunogenetics
• Genetic Heterogeneity
• Endophenotypes