Perioperative Systemic Stress Phenotypes Predict Immune Recovery Failure, Molecular Residual Disease, and Long-Term Outcomes After Colorectal Cancer Surgery: A Prospective Cohort Study.

Abstract excerpt

BACKGROUND: A major surgery represents a profound psychoneuroendocrine stressor that elicits coordinated inflammatory, immune, and metabolic responses. Although acute stress-related immune dysregulation is well-recognized, whether the magnitude and persistence of perioperative systemic stress phenotypes are associated with immune recovery failure, molecular residual disease (MRD), and long-term clinical outcomes,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Aged
• Share to Colorectal Neoplasms