Psychological resilience and its genetic determinants: Insights from longitudinal analyses of surgery and trauma cohorts.

doi:10.1017/S0033291726105790

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Article

Psychological resilience and its genetic determinants: Insights from longitudinal analyses of surgery and trauma cohorts.

Psychological medicine - 21 Sept 2026

Wang Hongxi, Zhang Yanan, Liu Lei, Yang Huazhen, Luo Jiesiwei, Cao Zian, Chen Wenwen, Zeng Yu, Fang Fang, Song Jie, Huang Jin, Li Qian, Song Huan

Abstract excerpt

BACKGROUND: To identify resilience to trauma using longitudinal psychological assessments and uncover its genetic components. METHODS: This prospective cohort study included 12,946 surgical patients from the China Surgery and Anesthesia Cohort (CSAC) with assessments of depressive symptoms from pre-surgery through 1, 6, and 12 months post-surgery, using the 9-item Patient Health Questionnaire (PHQ-9). Linear...

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Topics

Humans
Female
Resilience, Psychological
Genome-Wide Association Study
Middle Aged
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Male

China

Longitudinal Studies

Prospective Studies

Adult

Depression

Wounds and Injuries

Source

Open in PubMed

Identifiers

PMID: 42765393
DOI: 10.1017/S0033291726105790

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SDK1

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