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Article

Perioperative NLR/PLR dynamic phenotypes and prediction of postoperative recurrence in locally advanced gastric cancer: a retrospective cohort study.

BMC cancer - 30 Jun 2026

Wu Yinxiao, Zhou Jie, Li Su, Xuan Ying, Cai Dongyan

Abstract excerpt

BACKGROUND: Systemic inflammation plays a critical role in tumor progression and postoperative recurrence in gastric cancer. The neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are readily accessible biomarkers of systemic inflammatory and immune responses, but their dynamic changes around surgery remain underexplored. This study aimed to assess the prognostic value of principal...

Read the complete abstract on PubMed

Topics

Humans
Stomach Neoplasms
Female
Retrospective Studies
Neoplasm Recurrence, Local
Male
Middle Aged

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Neutrophils

Prognosis

Phenotype

Aged

Lymphocytes

Gastrectomy

Principal Component Analysis

Blood Platelets

Lymphocyte Count

Platelet Count

Disease-Free Survival

Source

Open in PubMed Open full text

Identifiers

PMID: 42380878
DOI: 10.1186/s12885-026-16431-2
PMCID: PMC13587439

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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