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Article

Identification of DHX58 as a potential therapeutic target for ovarian cancer through multi-omics Mendelian randomization and transcriptomic data analysis.

Journal of ovarian research - 30 Mar 2026

Chen Yanbin, Ma Fengyan, Huang Xifeng, Zhuang Zhemin, Lin Likun, Liao Yuming, Wang Jinhong

Abstract excerpt

BACKGROUND: Ovarian cancer (OC), a prevalent malignancy of the female reproductive system, is significantly impacted by drug resistance, which reduces treatment efficacy and worsens patient survival. Therefore, identifying broader therapeutic targets is crucial for improving treatment outcomes in OC patients. METHODS: The research project utilized Mendelian randomization (MR) analysis and summary data-based...

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Identifiers

PMID: 41913250
DOI: 10.1186/s13048-026-02084-z
PMCID: PMC13154425

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DHX58

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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