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Molecular characteristics of early- and late-onset ovarian cancer: insights from multidimensional evidence

23 Apr 2025

Abstract excerpt

BACKGROUND: Ovarian cancer (OC) is among the most lethal gynecologic malignancies, characterized by poor prognosis. While aging is a well-established risk factor, the underlying mechanisms distinguishing early- and late-onset ovarian cancer remain poorly understood. METHODS: This study analyzed the global burden and age-related trends of ovarian cancer using the GBD database. A cut-off age of 55 years was used to...

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PMID: 40269926
DOI: 10.1186/s13048-025-01664-9

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