Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identifying therapeutic targets for primary ovarian insufficiency through integrated genomic analyses.

Journal of ovarian research - 2 Oct 2024

Du Haihong, Zeng Pengfei, Liu Xuyi, Zhang Jun, Huang Zhonglu

Abstract excerpt

BACKGROUND: Primary ovarian insufficiency (POI) is a disorder characterized by the premature decline in ovarian function, leading to significant fertility and health impacts on women under 40. The unclear etiology of POI hinders the development of effective treatments, highlighting the need for novel therapeutic targets. METHODS: This study employed genome-wide association analysis (GWAS) integrated with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Predisposition to Disease
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genomics

Share to Polymorphism, Single Nucleotide

Share to Primary Ovarian Insufficiency

Share to Quantitative Trait Loci

Source

Open in PubMed Open full text

Identifiers

PMID: 39358799
DOI: 10.1186/s13048-024-01524-y
PMCID: PMC11446024

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identifying therapeutic targets for primary ovarian insufficiency through integrated genomic analyses.PMID 39358799Read ↗

Genetic landscape of a large cohort of Primary Ovarian Insufficiency: New genes and pathways and implications for personalized medicineSemantic proximity Read ↗

Genetic Landscape of a Cohort of 120 Patients with Diminished Ovarian Reserve: Correlation with InfertilitySemantic proximity Read ↗

Genetics of Primary Ovarian Insufficiency in the Next-Generation Sequencing EraSemantic proximity Read ↗

Prioritization of potential drug targets in ovarian-related diseases: Mendelian randomization and colocalization analyses.Semantic proximity Read ↗

Genetics of ovarian insufficiency and defects of folliculogenesis.Semantic proximity Read ↗

Therapeutic targets for endometriosis: Genome-wide Mendelian randomization and colocalization analyses.Semantic proximity Read ↗

Screening of targeted panel genes in Brazilian patients with primary ovarian insufficiencySemantic proximity Read ↗

Systematic mapping and in silico reevaluation of genomic copy number variations in primary ovarian insufficiency.Semantic proximity Read ↗

A Tiered Approach to Exome Sequencing Analysis in Early-Onset Primary Ovarian Insufficiency.Semantic proximity Read ↗

Integrative Bioinformatics Analysis for Identifying the Mitochondrial-Related Gene Signature Associated with Immune Infiltration in Premature Ovarian InsufficiencySemantic proximity Read ↗

Genetics of primary ovarian insufficiency: new developments and opportunities.Semantic proximity Read ↗

Whole-exome sequencing in patients with premature ovarian insufficiency: early detection and early interventionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.