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Article

Association between circulating inflammatory cytokine levels and the risk of polymyositis: A bidirectional Mendelian randomization study.

International reviews of immunology - 1 Jan 2026

Shao Jiang, Xie Jinjiao, Zheng Xiaoli, Luo Xiongyan, Xiong Anji

Abstract excerpt

BACKGROUND: Analyses of the association between circulating inflammatory cytokine levels and polymyositis (PM) remains challenging because of the limitations of traditional observational studies. Therefore, we used Mendelian randomization (MR) to assess the causal relationship between the levels of 41 circulating inflammatory cytokines and the risk of PM. METHODS: Using pooled data from genome-wide association...

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PMID: 41910242
DOI: 10.1080/08830185.2026.2650140

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