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Exploring the causal link between circulating cytokines and sarcopenia traits: A Mendelian randomization analysis.

Environmental toxicology - 1 Jun 2024

Di Wang, Luyao Yang, Chengwei Yang, Valtonen Anu M, Juha-Pekka Kulmala, Ying Gao

Abstract excerpt

BACKGROUND: Previous observational studies have linked circulating cytokines to sarcopenia, but their causal relationship remains unclear. This study employed Mendelian Randomization (MR) to investigate the causal links between circulating cytokines and sarcopenia-related traits using genetic data. METHODS: A two-sample bidirectional MR analysis was conducted using data from individuals of European ancestry,...

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Cytokines
HGF gene
Genome-Wide Association Study
Hand Strength
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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PMID: 38450985
DOI: 10.1002/tox.24206

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HGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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