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Article

Associations of the circulating levels of cytokines with the risk of myeloproliferative neoplasms: a bidirectional mendelian-randomization study.

BMC cancer - 26 Apr 2024

Xiong Hao, Zhang Huitao, Bai Jun, Li Yanhong, Li Lijuan, Zhang Liansheng

Abstract excerpt

OBJECTIVE: In the pathogenesis of myeloproliferative neoplasms (MPN), inflammation plays an important role. However, it is unclear whether there is a causal link between inflammation and MPNs. We used a bidirectional, two-sample Mendelian randomization (MR) approach to investigate the causal relationship between systemic inflammatory cytokines and myeloproliferative neoplasms. METHODS: A genome-wide association...

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Identifiers

PMID: 38671390
DOI: 10.1186/s12885-024-12301-x
PMCID: PMC11046808

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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