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Genetic Variants Associated with Non-Steroidal Anti-Inflammatory Drug-Induced Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.

Medical sciences (Basel, Switzerland) - 19 Feb 2026

Kosanlawit Jenita, Konyoung Parinya, Amornpinyo Warayuwadee, Tassaneeyakul Wichittra, Kanjanawart Sirimas, Pattanacheewapull Oranuch, Purimart Danklai, Nakkam Nontaya

Abstract excerpt

Background/Objectives: Non-steroidal anti-inflammatory drugs (NSAIDs) are widely prescribed to help alleviate pain and treat inflammation, but they are also recognized as common causes of severe cutaneous adverse reactions (SCARs), including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). Despite their clinical importance, pharmacogenetic markers to predict individual susceptibility to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41892813
DOI: 10.3390/medsci14010098
PMCID: PMC13028346

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CYP2C9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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