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Article

Genome-wide association study of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Europe

1 Jan 2011

Abstract excerpt

BACKGROUND: Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare but extremely severe cutaneous adverse drug reactions in which drug-specific associations with HLA-B alleles were described. OBJECTIVES: To investigate genetic association at a genome-wide level on a large sample of SJS/TEN patients. METHODS: We performed a genome wide association study on a sample of 424 European cases and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21801394
DOI: 10.1186/1750-1172-6-52

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