Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HIV-1 gag genotypic resistance testing using short-read and long-read next-generation sequencing technologies.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jun 2026

Vellas Camille, Poiteau Lila, Raymond Stéphanie, Carcenac Romain, Ranger Noémie, Demmou Sofia, Mohammed Sofiane, Delobel Pierre, Izopet Jacques

Abstract excerpt

INTRODUCTION: Lenacapavir is a new antiretroviral agent that targets the HIV-1 capsid, and is currently indicated for the treatment of patients with multidrug-resistant infection. It was recently approved by the U.S. Food Drug and Administration for use in pre-exposure prophylaxis. A robust sequencing method to determine HIV-1 gag sequences and resistance-associated mutations (RAMs) in people living with HIV-1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-HIV Agents
Share to Drug Resistance, Viral

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to gag Gene Products, Human Immunodeficiency Virus

Share to Genotyping Techniques

Share to High-Throughput Nucleotide Sequencing

Share to HIV Infections

Share to RNA, Viral

Source

Identifiers

PMID: 41886877
DOI: 10.1016/j.jcv.2026.105939

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HIV-1 gag genotypic resistance testing using short-read and long-read next-generation sequencing technologies.PMID 41886877Read ↗

Comparison of short-read and long-read next-generation sequencing technologies for determining HIV-1 drug resistance.Semantic proximity Read ↗

Sensitive HIV-1 DNA Pol Next-Generation Sequencing for the Characterisation of Archived Antiretroviral Drug Resistance.Semantic proximity Read ↗

Design and Evaluation of Next-Generation HIV Genotyping for Detection of Resistance Mutations to 28 Antiretroviral Drugs Across 5 Major Classes Including Lenacapavir.Semantic proximity Read ↗

Rapid HIV-1 genotyping assay for the detection of capsid mutations.Semantic proximity Read ↗

Technologies for HIV-1 drug resistance testing: inventory and needs.Semantic proximity Read ↗

Deep sequencing for HIV-1 clinical management.Semantic proximity Read ↗

HIV-1 genotypic resistance testing using single molecule real-time sequencing.Semantic proximity Read ↗

Evaluation of HIV-1 capsid genetic variability and lenacapavir (GS-6207) drug resistance-associated mutations according to viral clades among drug-naive individuals.Semantic proximity Read ↗

G-HIV: An Integrated Long-Read Sequencing and Automated Bioinformatics Platform for Rapid and Precise HIV-1 SurveillanceSemantic proximity Read ↗

HIV-1 Drug Resistance Genotyping in Resource Limited Settings: Current and Future Perspectives in Sequencing Technologies.Semantic proximity Read ↗

Lenacapavir treatment-emergent HIV-1 capsid resistance mutations are frequently associated with replication defects.Semantic proximity Read ↗

Portable Nanopore sequencing solution for next-generation HIV drug resistance testing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.