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Article

Portable Nanopore sequencing solution for next-generation HIV drug resistance testing.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Apr 2024

Park Sung Yong, Faraci Gina, Ganesh Kevin, Dubé Michael P, Lee Ha Youn

Abstract excerpt

BACKGROUND: Tackling HIV drug resistance is one of major challenges for ending AIDS epidemic, but the elevated expense of cutting-edge genomics hampers the advancement of HIV genotype testing for clinical care. METHODS: We developed a HIV genotype testing pipeline that centers on a cost-efficient portable Nanopore sequencer. Accuracy verification was conducted through comparison with parallel data obtained via...

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Identifiers

PMID: 38219684
DOI: 10.1016/j.jcv.2024.105639
PMCID: PMC10947882

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