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Article

Comparison of short-read and long-read next-generation sequencing technologies for determining HIV-1 drug resistance.

Journal of medical virology - 1 Oct 2024

Vellas Camille, Doudou Amira, Mohamed Sofiane, Raymond Stéphanie, Jeanne Nicolas, Latour Justine, Demmou Sofia, Ranger Noémie, Gonzalez Dimitri, Delobel Pierre, Izopet Jacques

Abstract excerpt

Accurate HIV-1 genome sequencing is necessary to identify drug resistance mutations (DRMs) in people with HIV-1 (PWH). Next-generation-sequencing (NGS) allows the detection of minor variants and is now available in many laboratories. Our study aimed to compare two NGS approaches, a "short read" sequencing protocol using DeepChek® Whole Genome HIV-1 Assay on Illumina, and a "long read" sequencing protocol of HIV-1...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 39387352
DOI: 10.1002/jmv.29951

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