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Article

Insights From Mutational and Transcriptomic Profiles in Epithelial-myoepithelial Carcinoma.

The American journal of surgical pathology - 1 Jul 2026

Alsugair Ziyad, Descotes Françoise, Champagnac Anne, Lopez Jonathan, Fieux Maxime, Philouse Pierre, Céruse Philippe, Thamphya Brice, Pissaloux Daniel, Tirode Franck, Benzerdjeb Nazim

Abstract excerpt

Epithelial-myoepithelial carcinoma (EMC) is a rare malignant tumor of the salivary glands, often characterized by HRAS mutations. The present study aimed to better define the molecular and transcriptomic landscape of EMC and explore its relationship with other head and neck neoplasms, particularly basal cell adenoma (BCA). We retrospectively analyzed 14 EMC cases using histology, immunohistochemistry, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41879968
DOI: 10.1097/PAS.0000000000002541
PMCID: PMC13263047

Genes

HRAS
GATA3
CHI3L1
FBXO32
GRIA2
HMGA2
MME
NOTCH1
PIK3CA
PLAG1
STAT5B
WIF1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

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