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Article

Foslip-Mediated Photodynamic Treatment Reprograms Macrophages Phenotype in Tri-Culture Head and Neck Cancer Spheroids.

International journal of nanomedicine - 1 Jan 2026

Francois Aurélie, Dirheimer Luca, Mastronicola Romina, Dolivet Gilles, Bezdetnaya Lina

Abstract excerpt

Background: The tumor microenvironment (TME) composition is among the critical events leading to the poor prognosis of head and neck cancers. TME includes immune cells, tumor-associated macrophages (TAMs), cancer-associated fibroblasts (CAF), and other non-cancerous cells, which contribute to therapeutic outcome. The heterogeneity of the TME offers a multitude of potential targets for photodynamic therapy (PDT)....

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Topics

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Share to Cell Line, Tumor
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 41873361
DOI: 10.2147/IJN.S562422
PMCID: PMC13006025

Genes

CD163
CD80

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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