Article
Extracellular vesicles mediated proinflammatory macrophage phenotype induced by radiotherapy in cervical cancer.
BMC cancer - 21 Jan 2022
Ren Junli, Li Lili, Yu Baofeng, Xu Enwei, Sun Naiping, Li Xiaoning, Xing Zihan, Han Xiaodong, Cui Yaqin, Wang Xiaoyan, Zhang Xiaoxue, Wang Guoliang
Abstract excerpt
BACKGROUND: Radiotherapy is a highly effective treatment for cervical cancer. Recent studies focused on the radiotherapy induced anti-tumor immunity. Whether tumor-derived extracellular vesicles (EVs) play roles in radiotherapy induced tumor associated macrophage (TAM) polarization remains unclear. MATERIALS AND METHODS: This study analysed the phenotype of macrophages in cancer tissue and peripheral blood of...
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