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Article

Tumour-associated macrophages are recruited and differentiated in the neoplastic stroma of oral squamous cell carcinoma.

Pathology - 1 Apr 2016

Essa Ahmed Abdelaziz Mohamed, Yamazaki Manabu, Maruyama Satoshi, Abé Tatsuya, Babkair Hamzah, Raghib Adel Mohamed, Megahed Eman Mohey El-Din, Cheng Jun, Saku Takashi

Abstract excerpt

To confirm our hypothesis that macrophages recruited to fight against oral squamous cell carcinoma (SCC) invasion are functionally differentiated within neoplastic stromata, we analysed arrangements of macrophage subtypes and cancer-associated fibroblasts (CAFs) in their association with blood vasculatures in the neoplastic stroma. Surgical specimens of oral SCC were immunohistochemically examined for macrophage...

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PMID: 27020496
DOI: 10.1016/j.pathol.2016.02.006

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