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Article

The BaeSR two-component system activates bamK, a paralog of the essential β-barrel foldase bamA, in Klebsiella pneumoniae.

mBio - 8 Apr 2026

Storek Kelly M, Reeder Janina, Sun Dawei, Yan Donghong, Murchison Austin K, Xu Min, Skippington Elizabeth, Rutherford Steven T

Abstract excerpt

β-Barrel outer membrane proteins (OMPs) perform critical functions in gram-negative bacteria including outer membrane biogenesis, nutrient acquisition, and efflux. OMPs are folded by the β-barrel assembly machinery (BAM) with BamA as a central and essential component. BamK, a Klebsiella pneumoniae BamA paralog, can functionally replace BamA; however, native bamK expression and a role for BamK have not been...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 41870142
DOI: 10.1128/mbio.03497-24
PMCID: PMC13059784

Genes

OMP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 12 Sept 2026.

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