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Article

The relationship between APOL1 risk variants and with preeclampsia and fetal outcomes.

Pregnancy hypertension - 1 Jun 2026

Afsar Baris, Afsar Rengin Elsurer, Lentine Krista L

Abstract excerpt

In people of African ancestry, carrying 2 Apolipoprotein L1 gene (APOL1) high-risk variants (G1/G1, G2/G2, or G1/G2) has been associated with increased risk of progressive chronic kidney disease, hypertension, HIV-associated nephropathy and focal segmental glomerulosclerosis. Recent studies suggest that the impact of APOL1 high-risk variants also affects pregnancy and fetal outcomes, including preeclampsia, low...

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Apolipoprotein L1
APOL1 gene
Genetic Predisposition to Disease
Pre-Eclampsia
Pregnancy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pregnancy Outcome

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Identifiers

PMID: 41865712
DOI: 10.1016/j.preghy.2026.101458

Genes

APOL1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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The relationship between APOL1 risk variants and with preeclampsia and fetal outcomes.PMID 41865712Read ↗

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