Article
Integrated drivers of basal and acute immunity in diverse human populations.
Cell reports. Medicine - 21 Apr 2026
Hegab Souquette Aisha, Allen E Kaitlynn, Oshansky Christine M, Rampersaud Evadnie, Walker Emily V, Tang Li, Wong Sook-San, Jeevan Trushar, Shi Lei, Pounds Stanley, Qu Jia-Hua, Elias George, Kuan Guillermina, Balmaseda Angel, Zapata Raul, Shaw-Saliba Kathryn, Van Damme Pierre, Van Tendeloo Viggo, Dib Juan Carlos, Crawford Jeremy Chase, Ogunjimi Benson, Webby Richard, Schultz-Cherry Stacey, Pekosz Andrew, Rothman Richard E, Gordon Aubree, Thomas Paul G
Abstract excerpt
Prior studies have identified genetic, infectious, and biological associations with immune competence and disease severity; however, there have been few integrative analyses of these factors. Here, we examine putative determinants of immunity, including single-nucleotide polymorphisms, genetic ancestry, race/ethnicity, herpesviruses, age, and gender. Healthy cohorts exhibit significant differences in cytokine...
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