Article

Multi-cohort analysis of host immune response identifies conserved protective and detrimental modules associated with severity irrespective of virus

2020-10-05

Abstract excerpt

SARS-CoV-2 pandemic, the fourth pandemic of the decade, has underscored gaps in global pandemic preparedness and the need for generalizable tests to avert overwhelming healthcare systems worldwide, irrespective of a virus. We integrated 4,780 blood transcriptome profiles from patients infected with one of 16 viruses across 34 independent cohorts from 18 countries, and 71 scRNA-seq profiles of 264,224 immune cells...

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Literature Corpus work: 14b41472-c76f-58ce-a434-ab4d6d0ce694
DOI: 10.1101/2020.10.02.20205880

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