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Host genetic ancestry and immunity to pathogens.

Trends in microbiology - 1 Jul 2026

Castanha Priscila M S, Martí Michelle M, Marques Ernesto T A, Martinson Jeremy J, Barratt-Boyes Simon M

Abstract excerpt

Recent studies have reported increased susceptibility to or reduced severity of viral and bacterial infections between distinct ancestral populations. In this review, we will outline the current state of knowledge regarding the interplay between genetic ancestry and the immune response to pathogens. We will concentrate on the ancestry-associated drivers of these immunological variations through the lens of...

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PMID: 41876293
DOI: 10.1016/j.tim.2026.02.007

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