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Article

Evolutionary dynamics of epitopes of limited variability on the head of influenza H1 haemagglutinin.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jun 2026

Lourenço José, Zinad Hany, Kempton James, Gupta Sunetra

Abstract excerpt

It is commonly assumed that naturally protective targets of immunity in influenza are highly variable. Theoretical work suggests, by contrast, that influenza evolution is primarily driven by naturally protective responses against epitopes of limited variability (ELV). At least one ELV has been identified on the head region of haemagglutinin of H1 influenza, opening up the possibility of producing a universal...

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Identifiers

PMID: 41856195
DOI: 10.1016/j.meegid.2026.105926

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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