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Article

Hypertriglyceridemia Does Not Worsen Thoracic Aortic Aneurysm and Dissection in GPIHBP1 Knockout Mice-Brief Report.

Arteriosclerosis, thrombosis, and vascular biology - 1 May 2026

Wang Banglong, Meng Zhe, Li Jiatian, Wu Feng, Song Baoshen, Huang Wei, Liao Jiawei

Abstract excerpt

BACKGROUND: Hypertriglyceridemia is an established risk factor for atherosclerotic cardiovascular disease and has recently been implicated in abdominal aortic aneurysm pathogenesis. However, its role in thoracic aortic aneurysm and dissection (TAAD) remains undefined. METHODS: We investigated the impact of hypertriglyceridemia on experimental TAAD using GPIHBP1 (glycosylphosphatidylinositol-anchored high-density...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41853866
DOI: 10.1161/ATVBAHA.126.324300

Genes

GPIHBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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