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Article

β-Aminopropionitrile monofumarate induces thoracic aortic dissection in C57BL/6 mice.

Scientific reports - 22 Jun 2016

Ren Weihong, Liu Yan, Wang Xuerui, Jia Lixin, Piao Chunmei, Lan Feng, Du Jie

Abstract excerpt

Thoracic aortic dissection (TAD) is a catastrophic disease with high mortality and morbidity, characterized by fragmentation of elastin and loss of smooth muscle cells. However, the underlying pathological mechanisms of this disease remain elusive because there are no appropriate animal models, limiting discovery of effective therapeutic strategies. We treated mice on C57BL/6 and FVB genetic backgrounds with...

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Identifiers

PMID: 27329825
DOI: 10.1038/srep28149
PMCID: PMC4916438

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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