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Article

Cytokine profiles, genetic polymorphisms, and systemic inflammatory markers in type 1 diabetes patients with COVID-19: IL-18 a predictor of disease severity.

Frontiers in immunology - 1 Jan 2026

Abdullah Mohammed Yousif, Laaribi Ahmed Baligh, Babay Wafa, Alhaddad Farah Abdulkhaleq Khattab, Mehri Asma, Ouzari Hadda-Imene, Marghali Sonia

Abstract excerpt

Background: Patients with Type 1 Diabetes Mellitus (T1DM) are at increased risk for severe COVID-19 due to chronic inflammation, immune dysregulation, and impaired antiviral responses. However, the combined contribution of cytokine imbalance, host genetic variation, and systemic inflammation on COVID-19 severity in this population remains incompletely understood. This study aimed to investigate inflammatory...

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Identifiers

PMID: 41846929
DOI: 10.3389/fimmu.2026.1736234
PMCID: PMC12989528

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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